… DPP-4 inhibitors with linear pharmacokinetics, linagliptin is … compared to patients with identified
diabetes prior the stroke (68… linagliptin versus glimepiride in patients with type 2 diabetes …

… We demonstrated that the DPP-4 inhibitor linagliptin … and improved neurological deficit
compared with control mice. … diabetes complicated with stroke [26, 27], suggesting that …

… -fed mice was treated with either linagliptin or glimepiride for … t test was used for the comparison
between the standard diet … Importantly, we demonstrated that Lina or Gli can counteract …

… -to-head comparison in both T2D/obese and normal mice by … day 3 after stroke) of T2D mice
with linagliptin or glimepiride … or additional DPP-4 substrates (41). Indeed, GLP-1 levels and …

… The DPP-4 inhibitor linagliptin and sulfonylurea glimepiride … DPP-4i can also reduce
stroke-induced brain damage in animal … by linagliptin, we performed a head-to-head comparison …

… ] and unfortunately failed to counteract the disease progression. … brain damage after stroke
in both normal and T2D/obese … in the Linagliptin 0.513 mg/kg group when compared with the …

… DPP-4 inhibitors are registered for treatment of diabetes mellitus type 2. They slow down …
with linagliptin had significantly fewer non-fatal stroke than those treated with glimepiride. …

… DPP-4 inhibitors, such as sitagliptin, alogliptin, or linagliptin, bind non… DPP-4 inhibitor
linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride…

… ,18) and may reduce brain damage following a stroke (19). In … Linagliptin is a selective,
once-daily DPP-4 inhibitor (21) with … 5 years), which compares linagliptin with glimepiride also on …

… -1) in the brain, and linagliptin improves functional outcomes of stroke in a manner dependent
on … of the DPP-4 inhibitor linagliptin compared with the sulfonylurea glimepiride. Although, …